Tuğçe Nihal GEVREK
Educational Background: 

B.Sc Marmara University , Chemical Education (2008)

M.Sc Boğaziçi University , Chemistry (2011)

Ph. D. Bogazici University, Dept. of Chemistry (2017)



Reactive polymeric surface coatings for biomedical applications.


1. Subramani, C.; Cengiz, N.; Saha,K.; Gevrek, T.N.;Yu,X.;Jeong, Y.; Bajaj, A.; Sanyal, A.; Rotello, V.M.

   ‘Direct Fabrication of Functional and Biofunctional Nanostructures Through Reactive Imprinting’

   Advanced Materials 2011, 23, 3165–3169.

2. Gevrek, T. N.; Ozdeslik, R. N.; Sahin, G. S.; Yesilbag, G.; Mutlu, S.; Sanyal, A.

   ‘Functionalization of Reactive Polymeric Coatings via Diels–Alder Reaction Using Microcontact Printing’

   Macromol. Chem. Phys. 2011, 13 (2) 166-172.

3. Gevrek, T. N.; Arslan, M.; Sanyal A.

‘Design and Synthesis of Maleimide Group Containing Polymeric Materials via the Diels-Alder/Retro Diels-Alder Strategy’

Functional Polymers by Post-Polymerization Modification 2012 Willey-VCH, 119-153. Theato, P.; Klok, H.-A (ed.).

4. Beria, L.; Gevrek, T. N.; Erdog, A.;   Sanyal, A.; Pasini, D.; Sanyal, A.

   ‘Clickable’ hydrogels for all: facile fabrication and functionalization’

   Biomater. Sci2014, 2, 67-75.

5. Arslan, M.; Gevrek, T. N.; Lyskawa, J.; Szunerits, S.; Boukherroub, R.; Sanyal, R.; Woisel, P.; Sanyal, A. 

‘Bioinspired Anchorable Thiol-reactive Polymers: Synthesis and Applications towards Surface Functionalization of Magnetic Nanoparticles’

   Macromolecules 2014, 47 (15), pp 5124–5134

6. Arslan, M.; Gevrek, T. N.; Sanyal, R.; Sanyal, A.

   ‘Fabrication of poly(ethylene glycol)-based cyclodextrin containing hydrogels via thiol-ene click reaction’

   European Polymer Journal 2015, 62, 426–434.

7. Arslan, M.; Gevrek, T. N.; Sanyal, A.; Sanyal, R.

‘Cyclodextrin mediated polymer coupling via thiol-maleimide conjugation: facile access to functionalizable hydrogels’

   RSC Adv. 2014, 4, 57834-57841.

8. Gevrek, T. N.; Bilgic, T.; Klok, H.-A.;Sanyal, A.

‘Maleimide-Functionalized Thiol Reactive Copolymer Brushes: Fabrication and Post-Polymerization Modification’

   Macromolecules, 2014, 47 (22), 7842–7851.

9. Park, E.-J.; Gevrek,T. N.; Sanyal, R.; Sanyal, A.

   ‘Indispensable Platforms for Bioimmobilization: Maleimide-Based Thiol Reactive Hydrogels’

   Bioconjugate Chem. 2014, 25 (11), 2004–2011.

10. Gevrek, T. N.; Sanyal A.

     ‘Thiol Based Conjugation: Polymerıc Material Modification’ 

     Encyclopedia of Biomedical Polymers and Polymeric Biomaterials Vol.1, 2015 Taylor & Francis, 7847-7883.

11. Dübner, M.; Gevrek, T. N.; Sanyal, A.; Spencer, N. D.; Padeste C.

‘Fabrication of Thiol–Ene “Clickable” Copolymer-Brush Nanostructures on Polymeric Substrates via Extreme Ultraviolet Interference Lithography’

     ACS Appl Mater Interfaces. 2015, 7 (21), 11337-11345.

12. Gok, O; Kosif, I; Dispinar, T; Gevrek, T. N.; Sanyal, R.; Sanyal, A.

‘Design and Synthesis of Water-Soluble Multifunctionalizable Thiol-Reactive Polymeric Supports for Cellular Targeting’

      Bioconjugate Chem2015, 26 (8), 1550-1560.

13. Kaga S., Gevrek T. N. Sanyal A., Sanyal R.

     ‘Synthesis and Functionalization of Dendron-Polymer Conjugate Based Hydrogels via Sequential Thiol-Ene “Click” Reactions.’       

     J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 926–934.

14. Kalaoglu-Altan,O.; Verbraeken, B.; Lava, K.; Gevrek, T. N.; Sanyal, R.; Dargaville, T.; De Clerck, K.; Hoogenboom, R.; Sanyal, A.

     ‘Multireactive Poly(2-oxazoline) Nanofibers through Electrospinning with Crosslinking on the Fly’ 

     ACS Macro Lett., 2016, 5 (6), 676-681.                                                                                                                                     

15. Oz, Y.; Arslan, M.; Gevrek, T. N.; Sanyal, R.; Sanyal, A.

‘Modular Fabrication of Polymer Brush Coated Magnetic Nanoparticles: Engineering the Interface for Targeted Cellular Imaging’

     ACS Appl Mater Interfaces, 2016, 8(30), 19813-19826.

16. Arslan, M.; Gevrek, T. N.; Sanyal, A.

     ‘Maleimide Containing Thiol-Reactive Polymers: Synthesis and Functionalization’ 

     Functional Polymers: Design, Synthesis, and Applications, 2016 Apple Academic Press.

17. Dübner, M.; Cadarso, V. J.; Gevrek, T. N.; Sanyal, A.; Spencer, N. D. and Padeste, C.

    ‘Reversible Light-Switching of Enzymatic Activity on Orthogonally Functionalized Polymer Brushes’

    ACS Applied Materials and Interfaces, 2017, 9 (11), 9245–9249.

18. Yuksekdag, Y. N.; Gevrek, T. N.; Sanyal, A.

     ‘Diels-Alder “Clickable” Polymer Brushes: A Versatile Catalyst-Free Conjugation Platform'

    ACS Macro Letters, 2017, 6, 415-420.

19. Cengiz N., Gevrek T. N, Sanyal R. and Sanyal A.

     ‘Orthogonal Thiol–ene ‘Click’ Reactions: A Powerful Combination for Fabrication and Functionalization of Patterned Hydrogels’

     Chemical Communications 2017, 8894-8897.

20. Gok, O., Erturk, P., Bolu, B. S., Gevrek, T. N., Sanyal, R. and Sanyal, A.

    ‘Dendrons and Multiarm Polymers with Thiol-Exchangeable Cores: A Reversible Conjugation Platform for Delivery’

    Biomacromolecules 2017, 18(8), 2463–2477.

21. Gevrek, T. N., Kosif, I., and Sanyal, A.

     ‘Surface-Anchored Thiol-Reactive Soft Interfaces: Engineering Effective Platforms for Biomolecular Immobilization and Sensing’

     ACS Applied Materials and Interfaces 2017, 9 (33), 27946–27954.

22.Gokbulut, B., Yartasi, E., Sunar, E., Kalaoglu-Altan, O. I., Gevrek, T. N., Sanyal, A. and Inci, M. N.

     ‘Humidity induced inhibition and enhancement of spontaneous emission of dye molecules in a single PEG nanofiber’

     Optical Materials Express 2018, 8(3), 568-580.

23. Gevrek, T. N., Cosar, M., Aydin, D., Kaga, E., Arslan, M., Sanyal, R. and Sanyal, A.

     ‘Facile Fabrication of a Modular “Catch and Release” Hydrogel Interface: Harnessing Thiol–Disulfide Exchange for Reversible Protein Capture and Cell Attachment’

     ACS Applied Materials and Interfaces 2018, 10(17), 14399-14409.

24. Gevrek, T. N., Yu, K., Kizhakkedathu, J. and Sanyal, A.

    'Thiol-Reactive Polymers for Titanium Interfaces: Fabrication of Antimicrobial Coatings'

     ACS Applied Polymer Materials  2019, 1(6), 1308-1316.

25. Mutlu, S., Unlu, K., Gevrek, T. N., and Sanyal, A.

     'Expanding the Versatility of Poly(dimethylsiloxane) through Polymeric Modification: An Effective Approach for Improving Triboelectric Energy Harvesting Performance'

     Smart Materials and Structures (IOP Science)  2020, 29(3), 035024.

26. Cengiz, N., Gevrek, T. N., Sanyal, R. and Sanyal, A.

     'Fabrication of Patterned Hydrogel Interfaces: Exploiting the Maleimide Group as a Dual Purpose Handle for Cross-Linking and Bioconjugation'

     Bioconjugate Chemistry, 2020, 31(5), 1382-1391.

27. Gevrek, T. N., Degirmenci, A., Sanyal, R. and Sanyal, A.

    ‘Multifunctional and Transformable ‘Clickable’ Hydrogel Coatings on Titanium Surfaces: From Protein Immobilization to Cellular Attachment’

    Polymers 2020, 12 (6), 1211.